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Production of l-alpha-amino acid

閱讀:121發(fā)布:2023-05-06

專利匯可以提供Production of l-alpha-amino acid專利檢索,專利查詢,專利分析的服務(wù)。并且PURPOSE: To obtain the titled substance, by reacting a D,L-α-amino acid amide with a culture fluid of a microorganism having L-α-aminoacid amide hydrolytic activity, etc. to give and L-α-amino acid and further racemizing the resultant D-α-amino acid amide to use the racemized D-α-amino acid amide as a raw material.
CONSTITUTION: D,L-α-amino acid amide is reacted with a culture fluid of a microorganism having L-α-amino acid amide hydrolytic activity, live microbial cells, dried microbial cells, treated microbial cells, etc. Examples of the microorganism include Schizosaccharomyces japonicus, Rhodosporodium toruloides, Candida humicola, Pseudomonas rosea, etc. The reaction solution contains L-α-amino acid and D-α-amino acid amide, and the latter is recovered and racemized in the presence of a strong basic substance while heating and converted into D,L-α-amino acid amide, which is circulated for use as a raw material for biochemical hydrolytic reaction to produce the aimed L-α-amino acid.
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